Depakote, used by adults and children older than 10, is a drug commonly prescribed to treat a variety of seizure and mood disorders, as well as migraine headaches. The drug is approved for use of children at 10 for seizure treatment and at 16 for migraine prevention. It is not approved to treat mood disorders in children.

While used during pregnancy, many women reported severe birth defects including:

  • Spina bifida and other spinal defects
  • Brain defects
  • Polydactyl growth
  • Malformation of face, skull or limbs
  • Malformation of cardiovascular system

Approved for distribution in 1983, Depakote is manufactured by Abbott Laboratories and commonly referred to as divalproex sodium and valproic acid.

There are related prescriptions to Depakote that include Depakene®, Depacon®, and Depakote ER® as well as generic brand names.